Neuroscience - CLA (NSCI)

Courses

NSCI 0817. Brain Matters. 3 Credit Hours.

One of the last frontiers in science is the brain. We know a great deal about the structure and function of the brain and nervous system, but it is challenging to comprehend fully the complexity of a system made up of 100 billion components that are interacting with one another using tens of trillions of connections that can change and rewire during development and aging. Neuroscience is the multidisciplinary field in which brain research falls. Neuroscience is one of the fastest growing domains in all of science - and good bet for a future career path. Neuroscientists investigate brain function from the level of molecular genetics, to cellular dynamics, to brain anatomy and physiology, to relations between brain, behavior, and cognition, to brain development and aging, to diseases of the brain. In this course, we will touch on knowledge about the brain at all these levels, and more. We will also discuss case studies of brain impairment. NOTE: This course fulfills a Science & Technology (GS) requirement for students under GenEd and Science & Technology Second Level (SB) for students under Core. Students cannot receive credit for this course if they have successfully completed Psychology 0817.

Course Attributes: GS

Repeatability: This course may not be repeated for additional credits.

NSCI 1051. Fundamentals of Neuroscience. 3 Credit Hours.

One of the last frontiers in science is the brain. Neuroscience is one of the fastest growing domains in all of science - and a good bet for a future career path. Neuroscientists investigate brain function from the level of molecular genetics, to cellular dynamics, to brain anatomy and physiology, to relations between brain, behavior and cognition, to brain development and aging, to diseases of the brain. In this course, we will touch on knowledge about the brain at all of these levels. The major course goal is to introduce you to neuroscience and its multidisciplinary dimensions.

Repeatability: This course may not be repeated for additional credits.

NSCI 1951. Honors Fundamentals of Neuroscience. 3 Credit Hours.

One of the last frontiers in science is the brain. Neuroscience is one of the fastest growing domains in all of science - and a good bet for a future career path. Neuroscientists investigate brain function from the level of molecular genetics, to cellular dynamics, to brain anatomy and physiology, to relations between brain, behavior and cognition, to brain development and aging, to diseases of the brain. In this course, we will touch on knowledge about the brain at all of these levels. The major course goal is to introduce you to neuroscience and its multidisciplinary dimensions. Note: Students who have received credit for NSCI 1051 will not receive additional credit for this course.

Cohort Restrictions: Must be enrolled in one of the following Cohorts: SCHONORS, UHONORS, UHONORSTR.

Course Attributes: HO

Repeatability: This course may not be repeated for additional credits.

NSCI 2001. Functional Neuroanatomy. 3 Credit Hours.

This course provides a broad overview of the structures of the brain and their function. Gross anatomy of the central nervous system will be covered. The organization of the major neural systems underlying sensory, motor, and cognitive function will be emphasized.

Repeatability: This course may not be repeated for additional credits.

Pre-requisites:
NSCI 1051|Minimum Grade of C-|May not be taken concurrently
OR NSCI 1951|Minimum Grade of C-|May not be taken concurrently.

NSCI 2121. Development/Plasticity/Repair. 3 Credit Hours.

The major aim of this course is to present the neurobiology of development from conception to birth and neurological and behavioral development in infancy and childhood. The initial emphasis is on embryonic and fetal development of the central nervous system and emergent behavioral plasticity. Sensory and motor developments in the fetus are examined. Postnatal development of the cerebral cortex and behavioral outcomes are explored in the context of environmental effects that can amplify or inhibit adaptive capacity. Biological (e.g., genetic) and environmental (e.g., parenting) influences on brain development of emotion and cognition are addressed. The tremendous plasticity of the brain is emphasized. Plasticity is the ability of the nervous system to respond to change. Neural malleability is maximal in early development, but the capacity for change and repair in the nervous system is maintained throughout life.

Repeatability: This course may not be repeated for additional credits.

Pre-requisites:
NSCI 1051|Minimum Grade of C-|May not be taken concurrently
OR NSCI 1951|Minimum Grade of C-|May not be taken concurrently.

NSCI 2122. Cellular Neuroscience. 3 Credit Hours.

An exciting scientific frontier is the molecular genetics and cellular dynamics of brain function. This course addresses phenomena at a cellular and molecular level that underlie brain plasticity and function. The cellular basis of the nervous system, some genetic factors involved in neural cell division and proliferation, proteins enabling neural receptor function, and molecules that comprise neurotransmitters will be covered. The molecular cascade that is initiated by glutamate release and responses of AMPA and NMDA receptors that results in genetic changes and structural formation of synapses is one example of molecular mechanisms to be addressed in this course.

Repeatability: This course may not be repeated for additional credits.

Pre-requisites:
NSCI 1051|Minimum Grade of C-|May not be taken concurrently
OR NSCI 1951|Minimum Grade of C-|May not be taken concurrently.

NSCI 2222. The Neurobiology of Disease. 3 Credit Hours.

Advances in basic neuroscience research have the potential to lead to understanding, treatment, and even cures for major nervous system disease. This course will provide students with state-of-the-art knowledge about applied neuroscience - the causes and treatment of some major diseases of the central nervous system. There is an emphasis on neuropathologies at all points of the life span - from diseases in infancy such as Phenylketonuria and Tay Sachs disease, to diseases in adulthood such as Multiple Sclerosis, AIDS and forms of demyelination caused by the JC virus, to neurodegenerative diseases of old age such as Alzheimer's disease and Parkinson's disease.

Repeatability: This course may not be repeated for additional credits.

Pre-requisites:
NSCI 1051|Minimum Grade of C-|May not be taken concurrently
OR NSCI 1951|Minimum Grade of C-|May not be taken concurrently.

NSCI 3000. Current Topics in Neuroscience. 3 Credit Hours.

The goal of this class is to explore in depth a current topic in neuroscience. Potential topics include addiction, schizophrenia, Alzheimer's disease, memory reconsolidation, and more. Note: A semester's course will cover one topic in depth and not cover multiple topics. In addition, students will also read primary literature (research articles), lead a 10 minute discussion on an article, write a review on a related topic, and present slides with their view. These exercises are intended to promote scientific analysis and the development of public speaking and writing skills.

Repeatability: This course may be repeated for additional credit.

Pre-requisites:
(NSCI 1051|Minimum Grade of C-|May not be taken concurrently
OR NSCI 1951|Minimum Grade of C-|May not be taken concurrently)
AND (PSY 1003|Minimum Grade of C-|May not be taken concurrently)
AND (NSCI 2001|Minimum Grade of C-|May not be taken concurrently)

NSCI 3005. Affective Neuroscience. 3 Credit Hours.

The brain is not just a thinking machine; it is also a feeling machine. This course explores the neural substrates behind emotions such as love, trust, fear, and pleasure. We will also discuss the relationship between emotions and cognition, the effect of emotions on animal and human behavior, and the biological basis of affective disorders such as anxiety and depression.

Repeatability: This course may not be repeated for additional credits.

Pre-requisites:
(PSY 2501|Minimum Grade of C-|May not be taken concurrently
OR PSY 2502|Minimum Grade of C-|May not be taken concurrently
OR NSCI 2001|Minimum Grade of C-|May not be taken concurrently)
AND (PSY 1003|Minimum Grade of C-|May not be taken concurrently)

NSCI 3006. Stress and the Brain. 3 Credit Hours.

Stress, in some form or other, is part of our everyday lives. How we respond to stress can either ensure our immediate survival or threaten long-term physical and mental well-being. This course will survey the clinical and preclinical research to understand how the brain initiates stress responses, and how stress, in turn, impacts the brain to alter behavior. The role that stress plays in the development of disorders, such as depression and post-traumatic stress disorder, will also be explored.

Repeatability: This course may not be repeated for additional credits.

Pre-requisites:
(PSY 2501|Minimum Grade of C-|May not be taken concurrently
OR PSY 2502|Minimum Grade of C-|May not be taken concurrently
OR NSCI 2001|Minimum Grade of C-|May not be taken concurrently)
AND (PSY 1003|Minimum Grade of C-|May not be taken concurrently)

NSCI 3087. Techniques in Neuroscience. 3 Credit Hours.

A major reason that neuroscience is such a dynamic and rapidly advancing field is that it relies on cutting edge technology. Throughout the history of neuroscience, advances have come with the development of new techniques. In this course, students will learn about a variety of traditional techniques in basic and clinical neuroscience as well as newly developed techniques driving the field to new insights. Methods to be discussed will be selected from among: genetic assays, genotyping, histology, immunohistochemistry, stereotaxic surgery, electrophysiology (patch clamping, single and multiple unit recording, EEG), behavioral assessment of animals, neuropsychological assessment in humans, human electrophysiology, transcranial magnetic stimulation, MRI and fMRI. From among identified neuroscience techniques, students will select one and prepare a demonstration or video.

Repeatability: This course may not be repeated for additional credits.

Pre-requisites:
(NSCI 1051|Minimum Grade of C-|May not be taken concurrently
OR NSCI 1951|Minimum Grade of C-|May not be taken concurrently)
AND (NSCI 2121|Minimum Grade of C-|May not be taken concurrently)
AND (NSCI 2122|Minimum Grade of C-|May not be taken concurrently)
AND (NSCI 2222|Minimum Grade of C-|May not be taken concurrently)

NSCI 3096. Conducting Neuroscience Research. 3 Credit Hours.

The objective of this writing intensive course is to develop critical thinking and analytical skills necessary for applying the scientific method in neuroscience. In the course, students will complete readings of primary sources, discuss literature, and participate in activities to strengthen research abilities. This experience will reinforce key methodological and statistical concepts that were taught earlier in the curriculum, while stimulating growth in understanding neuroscience and research processes in general. Students will present reports in writing and in class presentations.

Course Attributes: WI

Repeatability: This course may not be repeated for additional credits.

Pre-requisites:
(NSCI 1051|Minimum Grade of C-|May not be taken concurrently
OR NSCI 1951|Minimum Grade of C-|May not be taken concurrently)
AND (PSY 1003|Minimum Grade of C-|May not be taken concurrently)

NSCI 3900. Honors Special Topics. 3 Credit Hours.

The goal of this Honors class is to explore in depth a current topic in neuroscience. Potential topics include addiction, schizophrenia, Alzheimer's disease, memory reconsolidation, and more. Note: A semester's course will cover one topic in depth and not cover multiple topics.

Cohort Restrictions: Must be enrolled in one of the following Cohorts: SCHONORS, UHONORS, UHONORSTR.

Course Attributes: HO

Repeatability: This course may be repeated for additional credit.

NSCI 4182. Independent Study in Neuroscience 1. 1 to 4 Credit Hour.

Neuroscience majors are encouraged to gain first-hand experience with research as provided by Independent Study. This course is available in the laboratories of neuroscience faculty members at Temple University listed on the Neuroscience web site: www.temple.edu/cla/neuroscience. Students will carry out supervised neuroscience research by observing and participating in ongoing research in the laboratory. This course requires the student to spend 3-4 hours per credit per week of a 14-week semester in the lab.

Field of Study Restrictions: Must be enrolled in one of the following Fields of study: Neuroscience.

Repeatability: This course may be repeated for additional credit.

Pre-requisites:
NSCI 1051|Minimum Grade of C-|May not be taken concurrently
OR NSCI 1951|Minimum Grade of C-|May not be taken concurrently.

NSCI 4191. Collaborative Research I. 1 to 4 Credit Hour.

Faculty advisor needed for research in a particular area. For projects outside Temple University, approval must be obtained through a faculty member who will handle the liaison with the outside institution and ensure uniformity of requirements.

Repeatability: This course may be repeated for additional credit.

NSCI 4197. Capstone in Neuroscience. 4 Credit Hours.

The focus of this capstone is a topic important to many domains in neuroscience. Different topics will be covered in different semesters. This course has two major components: (1) instruction and practice on scientific writing of research papers and proposals, and instruction and practice on oral presentations; (2) Integration of content in basic and clinical neuroscience. The course will allow students to follow issues in neuroscience from cellular and molecular levels to translation and application in human life. The emphasis is on synthesis and application of material learned in the neuroscience major. NOTE: This course is limited to neuroscience majors in their senior year.

Field of Study Restrictions: Must be enrolled in one of the following Fields of study: Neuroscience.

Course Attributes: WI

Repeatability: This course may not be repeated for additional credits.

Pre-requisites:
NSCI 3087|Minimum Grade of C-|May not be taken concurrently.

NSCI 4282. Independent Study in Neuroscience 2. 1 to 4 Credit Hour.

Neuroscience majors are encouraged to gain first-hand experience with research as provided by Independent Study and may take up to 8 independent study credits. Independent Study in Neuroscience 2 follows Neuroscience 4182, Independent Study in Neuroscience 1, and can be taken in the same laboratory or in another lab of a neuroscience faculty member at Temple University. Faculty members sponsoring this course are listed on the Neuroscience web site: www.temple.edu/cla/neuroscience. Students will carry out supervised neuroscience research by observing and participating in ongoing research. This course requires the student to spend 3-4 hours per credit per week of a 14-week semester in the lab.

Field of Study Restrictions: Must be enrolled in one of the following Fields of study: Neuroscience.

Repeatability: This course may be repeated for additional credit.

Pre-requisites:
NSCI 1051|Minimum Grade of C-|May not be taken concurrently
OR NSCI 1951|Minimum Grade of C-|May not be taken concurrently.

NSCI 4291. Collaborative Research II. 1 to 4 Credit Hour.

Faculty advisor needed for research in a particular area. For projects outside Temple University, approval must be obtained through a faculty member who will handle the liaison with the outside institution and ensure uniformity of requirements.

Repeatability: This course may be repeated for additional credit.

NSCI 5001. Systems and Behavioral Neuroscience. 3 Credit Hours.

The goals of this class are to expose Master's degree students to topics in systems and behavioral neuroscience. In addition, students will also be introduced to methods and techniques used for the analysis of neural and behavioral data. Through intensive instruction of systems underpinning sensory, motor, and integrative functions, as well as motivation, students will gain a thorough understanding of brain function/behavior and its neuronal correlates.

Level Registration Restrictions: Must be enrolled in one of the following Levels: Graduate.

Repeatability: This course may not be repeated for additional credits.

NSCI 5002. Neurochemistry. 3 Credit Hours.

This course explores the major areas of cellular and molecular neurobiology, including cellular and subcellular components of the nervous system, neuronal excitability and molecular properties of ion channels, biochemistry of synaptic transmission, intracellular signaling, neurochemistry of learning and memory, cell injury and inflammation and psychiatric/neurodegenerative disorders. Material includes lectures, presentations and discussion of primary literature and journal articles that cover recent advances in the field. Additionally, students will get the opportunity to gain hands-on experience with some of the research methodologies used to study neurochemical processes.

Level Registration Restrictions: Must be enrolled in one of the following Levels: Graduate.

Repeatability: This course may not be repeated for additional credits.

NSCI 5016. Professional Development in Neuroscience. 3 Credit Hours.

This course will help prepare you for the remainder of your master's degree by providing the required laboratory and animal training, laboratory technique training, research and presentation skills training, and discussion of ethical issues in the field. The first module of this course will cover all the necessary laboratory and animal training and the second module will expose students to contemporary neuroscience techniques. The third module will provide training in research and presentation skills including how to design a research study, write a research paper and presenting your results. In the fourth module, we will discuss the ethical issues in neuroscience and consider the future challenges that may arise from the evolving study of the genetic and neurobiological determinants of behavior.

Level Registration Restrictions: Must be enrolled in one of the following Levels: Graduate.

Repeatability: This course may not be repeated for additional credits.

NSCI 8007. Neuroendocrinology. 3 Credit Hours.

This course will provide an in-depth exploration of the interactions between the endocrine system and the nervous system. The role of hormones in modulating behaviors and mental processes will be covered with the following topics: sex determination and differentiation, reproduction, parental behavior, social behavior, homeostasis, biological rhythms, stress, learning and memory, and affect. Multidisciplinary approaches to understand neuroendocrine function and dysfunction from the molecular to systems level will be covered.

Level Registration Restrictions: Must be enrolled in one of the following Levels: Graduate.

Repeatability: This course may not be repeated for additional credits.

NSCI 8008. Neuropsychopathology. 3 Credit Hours.

This course will provide an in-depth exploration of neuropsychopathology. Students will learn about recent advances in the understanding of the neurobiology mechanisms that underlie psychiatric disease, neurodegenerative, and neurological disorders. How available and experimental treatments for these disorders work also will be covered.

Level Registration Restrictions: Must be enrolled in one of the following Levels: Graduate.

Repeatability: This course may not be repeated for additional credits.

NSCI 8009. Neuroscience Drug Discovery. 3 Credit Hours.

This course will consist of a series of didactic sessions and seminar-style discussions on topics that cover major aspects of the drug discovery process including lead/target identification, validation, preclinical pharmacology, toxicity and clinical trials. The course will also address unique challenges of research translation from preclinical to early and late phases of clinical development. Additionally, the technical and clinical aspects of biomarker validation needed to be applied to the different aspects of drug development process will be discussed.

Level Registration Restrictions: Must be enrolled in one of the following Levels: Graduate.

Repeatability: This course may not be repeated for additional credits.

NSCI 9381. Readings in Neuroscience. 1 Credit Hour.

Level Registration Restrictions: Must be enrolled in one of the following Levels: Graduate.

Repeatability: This course may be repeated for additional credit.

NSCI 9991. Directed Research. 1 to 6 Credit Hour.

This course is intended to meet the needs of students who desire to carry on an individual investigation while working towards the Master's degree in Neuroscience.

Level Registration Restrictions: Must be enrolled in one of the following Levels: Graduate.

Repeatability: This course may be repeated for additional credit.